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Showing posts from March, 2025

H5N1 Update

Image
By Ahmed Mostafa, Elsayed M. Abdelwhab, Thomas C. Mettenleiter, and Stephan Pleschka - mdpi.com/1999-4915/10/9/497/htm, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=92987475 H5N1, bird flu, continues to infect wild and domestic birds, cattle, cats, and humans. So far, luck has been with us and H5N1 hasn't become a serious threat to humans. That is unless you don't consider the price of eggs and the contribution that issue made to the current chaos and incompetence in Washington DC. On Feb. 28, 2025, I downloaded 6,623 H5N1 HA sequences in FASTA format from GISAID  in order to look at the current state of mutations in the virus data. The analysis below is similar to posts here and here . I read the sequences into a dataframe with the FASTA header information becoming the columns of the dataframe.  > df_2025_02_28 <- fasta2dataframe( "data/gisaid_epiflu_sequence_HA_2025_02_28.fasta" ) The fasta2dataframe function is described in this post ...